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BDBM50228674 5,7-dichloro-3-(4-methoxy-3-nitrophenyl)-3-methylquinoline-2,4(1H,3H)-dione::CHEMBL253097

SMILES: COc1ccc(cc1[N+]([O-])=O)C1(C)C(=O)Nc2cc(Cl)cc(Cl)c2C1=O

InChI Key: InChIKey=LGLKATODTQDQGB-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50228674   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50228674
PNG
(5,7-dichloro-3-(4-methoxy-3-nitrophenyl)-3-methylq...)
Show SMILES COc1ccc(cc1[N+]([O-])=O)C1(C)C(=O)Nc2cc(Cl)cc(Cl)c2C1=O |w:11.12|
Show InChI InChI=1S/C17H12Cl2N2O5/c1-17(8-3-4-13(26-2)12(5-8)21(24)25)15(22)14-10(19)6-9(18)7-11(14)20-16(17)23/h3-7H,1-2H3,(H,20,23)
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PC cid
PC sid
UniChem

Patents

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from human cloned 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 18: 738-43 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.045
BindingDB Entry DOI: 10.7270/Q2XK8F99
More data for this
Ligand-Target Pair