BDBM50228908 3'-fluoro-4'-{2-[2-(4-methoxy-phenyl)-5-trifluoromethyl-2H-pyrazol-3-yl]-2-oxo-ethyl}-biphenyl-2-sulfonic acid amide::CHEMBL252650

SMILES: COc1ccc(cc1)-n1nc(cc1C(=O)Cc1ccc(cc1F)-c1ccccc1S(N)(=O)=O)C(F)(F)F

InChI Key: InChIKey=OJRDXFSQWLVJDP-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50228908   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50228908 (3'-fluoro-4'-{2-[2-(4-methoxy-phenyl)-5-trifluorom...) Show SMILES COc1ccc(cc1)-n1nc(cc1C(=O)Cc1ccc(cc1F)-c1ccccc1S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C25H19F4N3O4S/c1-36-18-10-8-17(9-11-18)32-21(14-24(31-32)25(27,28)29)22(33)13-16-7-6-15(12-20(16)26)19-4-2-3-5-23(19)37(30,34)35/h2-12,14H,13H2,1H3,(H2,30,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem Lett 18: 749-54 (2008) Article DOI: 10.1016/j.bmcl.2007.11.040 BindingDB Entry DOI: 10.7270/Q2DV1KQS
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50228908 (3'-fluoro-4'-{2-[2-(4-methoxy-phenyl)-5-trifluorom...) Show SMILES COc1ccc(cc1)-n1nc(cc1C(=O)Cc1ccc(cc1F)-c1ccccc1S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C25H19F4N3O4S/c1-36-18-10-8-17(9-11-18)32-21(14-24(31-32)25(27,28)29)22(33)13-16-7-6-15(12-20(16)26)19-4-2-3-5-23(19)37(30,34)35/h2-12,14H,13H2,1H3,(H2,30,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human thrombin				Bioorg Med Chem Lett 18: 749-54 (2008) Article DOI: 10.1016/j.bmcl.2007.11.040 BindingDB Entry DOI: 10.7270/Q2DV1KQS
					More data for this Ligand-Target Pair