BDBM50228910 2-[2'-((S)-3-hydroxy-pyrrolidin-1-ylmethyl)-biphenyl-4-yl]-1-[2-(4-methoxy-phenyl)-5-trifluoromethyl-2H-pyrazol-3-yl]-ethanone::CHEMBL402167

SMILES: COc1ccc(cc1)-n1nc(cc1C(=O)Cc1ccc(cc1)-c1ccccc1CN1CC[C@H](O)C1)C(F)(F)F

InChI Key: InChIKey=MHMSYXOVNQSRJW-DEOSSOPVSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50228910   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50228910 (2-[2'-((S)-3-hydroxy-pyrrolidin-1-ylmethyl)-biphen...) Show SMILES COc1ccc(cc1)-n1nc(cc1C(=O)Cc1ccc(cc1)-c1ccccc1CN1CC[C@H](O)C1)C(F)(F)F Show InChI InChI=1S/C30H28F3N3O3/c1-39-25-12-10-23(11-13-25)36-27(17-29(34-36)30(31,32)33)28(38)16-20-6-8-21(9-7-20)26-5-3-2-4-22(26)18-35-15-14-24(37)19-35/h2-13,17,24,37H,14-16,18-19H2,1H3/t24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem Lett 18: 749-54 (2008) Article DOI: 10.1016/j.bmcl.2007.11.040 BindingDB Entry DOI: 10.7270/Q2DV1KQS
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50228910 (2-[2'-((S)-3-hydroxy-pyrrolidin-1-ylmethyl)-biphen...) Show SMILES COc1ccc(cc1)-n1nc(cc1C(=O)Cc1ccc(cc1)-c1ccccc1CN1CC[C@H](O)C1)C(F)(F)F Show InChI InChI=1S/C30H28F3N3O3/c1-39-25-12-10-23(11-13-25)36-27(17-29(34-36)30(31,32)33)28(38)16-20-6-8-21(9-7-20)26-5-3-2-4-22(26)18-35-15-14-24(37)19-35/h2-13,17,24,37H,14-16,18-19H2,1H3/t24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human thrombin				Bioorg Med Chem Lett 18: 749-54 (2008) Article DOI: 10.1016/j.bmcl.2007.11.040 BindingDB Entry DOI: 10.7270/Q2DV1KQS
					More data for this Ligand-Target Pair