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BDBM50228936 6-chloro-N-(1-(2-fluoro-4-(1H-pyrazol-1-yl)phenyl)-2-oxopyrrolidin-3-yl)naphthalene-2-sulfonamide::CHEMBL404219

SMILES: Fc1cc(ccc1N1CCC(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O)-n1cccn1

InChI Key: InChIKey=ILGUTMWZAPDUFC-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50228936   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50228936
PNG
(6-chloro-N-(1-(2-fluoro-4-(1H-pyrazol-1-yl)phenyl)...)
Show SMILES Fc1cc(ccc1N1CCC(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O)-n1cccn1 |w:10.11|
Show InChI InChI=1S/C23H18ClFN4O3S/c24-17-4-2-16-13-19(6-3-15(16)12-17)33(31,32)27-21-8-11-28(23(21)30)22-7-5-18(14-20(22)25)29-10-1-9-26-29/h1-7,9-10,12-14,21,27H,8,11H2
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PC cid
PC sid
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Article
PubMed
2.70n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of human F10a by fluorescence assay


Bioorg Med Chem Lett 18: 23-7 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.023
BindingDB Entry DOI: 10.7270/Q2SX6CZF
More data for this
Ligand-Target Pair