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SMILES: CC(C)(C)c1ccccc1-c1ccc(nc1)N1CCC(NS(=O)(=O)\C=C\c2ccc(Cl)s2)C1=O

InChI Key: InChIKey=AIAUAKCFSNYUQF-FYWRMAATSA-N

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50228942   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))		BDBM50228942
PNG
((E)-N-(1-(5-(2-tert-butylphenyl)pyridin-2-yl)-2-ox...)
Show SMILES CC(C)(C)c1ccccc1-c1ccc(nc1)N1CCC(NS(=O)(=O)\C=C\c2ccc(Cl)s2)C1=O |w:19.21|
Show InChI InChI=1S/C25H26ClN3O3S2/c1-25(2,3)20-7-5-4-6-19(20)17-8-11-23(27-16-17)29-14-12-21(24(29)30)28-34(31,32)15-13-18-9-10-22(26)33-18/h4-11,13,15-16,21,28H,12,14H2,1-3H3/b15-13+
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Similars
Article
PubMed
 2.33E+3n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of human F10a by chromogenic assay

Bioorg Med Chem Lett 18: 23-7 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.023
BindingDB Entry DOI: 10.7270/Q2SX6CZF
More data for this
Ligand-Target Pair