BDBM50228943 6-chloro-naphthalene-2-sulfonic acid [1-(3-fluoro-biphenyl-4-yl)-2-oxo-pyrrolidin-3-yl]-amide::CHEMBL404708

SMILES: Fc1cc(ccc1N1CCC(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O)-c1ccccc1

InChI Key: InChIKey=ZDBTYHSHLLRKTK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50228943   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50228943 (6-chloro-naphthalene-2-sulfonic acid [1-(3-fluoro-...) Show SMILES Fc1cc(ccc1N1CCC(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O)-c1ccccc1 |w:10.11| Show InChI InChI=1S/C26H20ClFN2O3S/c27-21-9-6-19-15-22(10-7-18(19)14-21)34(32,33)29-24-12-13-30(26(24)31)25-11-8-20(16-23(25)28)17-4-2-1-3-5-17/h1-11,14-16,24,29H,12-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	215	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human F10a by fluorescence assay				Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF
					More data for this Ligand-Target Pair