BDBM50228949 6-chloro-N-(1-(2-fluoro-4-(1H-imidazol-1-yl)phenyl)-2-oxopyrrolidin-3-yl)naphthalene-2-sulfonamide::CHEMBL402077

SMILES: Fc1cc(ccc1N1CCC(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O)-n1ccnc1

InChI Key: InChIKey=UMZRAXUPAKFDQI-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50228949   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50228949 (6-chloro-N-(1-(2-fluoro-4-(1H-imidazol-1-yl)phenyl...) Show SMILES Fc1cc(ccc1N1CCC(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O)-n1ccnc1 |w:10.11| Show InChI InChI=1S/C23H18ClFN4O3S/c24-17-3-1-16-12-19(5-2-15(16)11-17)33(31,32)27-21-7-9-29(23(21)30)22-6-4-18(13-20(22)25)28-10-8-26-14-28/h1-6,8,10-14,21,27H,7,9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human F10a by fluorescence assay				Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF
					More data for this Ligand-Target Pair