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BDBM50228953 5-chloro-benzofuran-2-sulfonic acid [1-(3-fluoro-2'-methanesulfonyl-biphenyl-4-yl)-2-oxo-pyrrolidin-3-yl]-amide::CHEMBL403453

SMILES: CS(=O)(=O)c1ccccc1-c1ccc(N2CCC(NS(=O)(=O)c3cc4cc(Cl)ccc4o3)C2=O)c(F)c1

InChI Key: InChIKey=RPEBFLBSZDYQHK-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50228953   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50228953
PNG
(5-chloro-benzofuran-2-sulfonic acid [1-(3-fluoro-2...)
Show SMILES CS(=O)(=O)c1ccccc1-c1ccc(N2CCC(NS(=O)(=O)c3cc4cc(Cl)ccc4o3)C2=O)c(F)c1 |w:17.18|
Show InChI InChI=1S/C25H20ClFN2O6S2/c1-36(31,32)23-5-3-2-4-18(23)15-6-8-21(19(27)13-15)29-11-10-20(25(29)30)28-37(33,34)24-14-16-12-17(26)7-9-22(16)35-24/h2-9,12-14,20,28H,10-11H2,1H3
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PC cid
PC sid
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Article
PubMed
6.20n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of human F10a by fluorescence assay


Bioorg Med Chem Lett 18: 23-7 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.023
BindingDB Entry DOI: 10.7270/Q2SX6CZF
More data for this
Ligand-Target Pair