BDBM50229270 CHEMBL306566

SMILES: CCO\C(O)=C1\C(C(C(=O)OCC)=C(C)N=C1C[S+]([O-])c1ccncc1)c1ccccc1C(F)(F)F

InChI Key: InChIKey=MSISEKAQQHTITK-ZNTNEXAZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229270   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus)	BDBM50229270 (CHEMBL306566) Show SMILES CCO\C(O)=C1\C(C(C(=O)OCC)=C(C)N=C1C[S+]([O-])c1ccncc1)c1ccccc1C(F)(F)F |c:15,t:12| Show InChI InChI=1S/C25H25F3N2O5S/c1-4-34-23(31)20-15(3)30-19(14-36(33)16-10-12-29-13-11-16)22(24(32)35-5-2)21(20)17-8-6-7-9-18(17)25(26,27)28/h6-13,21,32H,4-5,14H2,1-3H3/b24-22+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Affinity to bind dihydropyridine receptor (DHP receptor) by inhibiting the radioligand [3H]nitrendipine				J Med Chem 34: 2248-60 (1991) BindingDB Entry DOI: 10.7270/Q27P91MK
					More data for this Ligand-Target Pair