null

SMILES: CCS(=O)(=O)CCN([C@H](C)c1nc2ccccc2n1-c1ccc(cc1)C#N)C(=O)Cc1ccc(F)c(c1)C(F)(F)F

InChI Key: InChIKey=CCUSUVZCBYDCHA-LJQANCHMSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50229379   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50229379 ((R)-N-(1-(1-(4-cyanophenyl)-1H-benzo[d]imidazol-2-...) Show SMILES CCS(=O)(=O)CCN([C@H](C)c1nc2ccccc2n1-c1ccc(cc1)C#N)C(=O)Cc1ccc(F)c(c1)C(F)(F)F Show InChI InChI=1S/C29H26F4N4O3S/c1-3-41(39,40)15-14-36(27(38)17-21-10-13-24(30)23(16-21)29(31,32)33)19(2)28-35-25-6-4-5-7-26(25)37(28)22-11-8-20(18-34)9-12-22/h4-13,16,19H,3,14-15,17H2,1-2H3/t19-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-IP-10 from CXCR3 receptor expressed in human PBMC in EDTA-anti-coagulated human plasma				Bioorg Med Chem Lett 18: 688-93 (2008) Article DOI: 10.1016/j.bmcl.2007.11.060 BindingDB Entry DOI: 10.7270/Q2WQ03HW
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50229379 ((R)-N-(1-(1-(4-cyanophenyl)-1H-benzo[d]imidazol-2-...) Show SMILES CCS(=O)(=O)CCN([C@H](C)c1nc2ccccc2n1-c1ccc(cc1)C#N)C(=O)Cc1ccc(F)c(c1)C(F)(F)F Show InChI InChI=1S/C29H26F4N4O3S/c1-3-41(39,40)15-14-36(27(38)17-21-10-13-24(30)23(16-21)29(31,32)33)19(2)28-35-25-6-4-5-7-26(25)37(28)22-11-8-20(18-34)9-12-22/h4-13,16,19H,3,14-15,17H2,1-2H3/t19-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-IP-10 from CXCR3 receptor expressed in human PBMC in RPMI-1640 buffer supplemented with 0.5% BSA				Bioorg Med Chem Lett 18: 688-93 (2008) Article DOI: 10.1016/j.bmcl.2007.11.060 BindingDB Entry DOI: 10.7270/Q2WQ03HW
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50229379 ((R)-N-(1-(1-(4-cyanophenyl)-1H-benzo[d]imidazol-2-...) Show SMILES CCS(=O)(=O)CCN([C@H](C)c1nc2ccccc2n1-c1ccc(cc1)C#N)C(=O)Cc1ccc(F)c(c1)C(F)(F)F Show InChI InChI=1S/C29H26F4N4O3S/c1-3-41(39,40)15-14-36(27(38)17-21-10-13-24(30)23(16-21)29(31,32)33)19(2)28-35-25-6-4-5-7-26(25)37(28)22-11-8-20(18-34)9-12-22/h4-13,16,19H,3,14-15,17H2,1-2H3/t19-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	521	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at CXCR3 assessed as ITAC-mediated migration of human PBMC in presence of 100% human plasma				Bioorg Med Chem Lett 18: 688-93 (2008) Article DOI: 10.1016/j.bmcl.2007.11.060 BindingDB Entry DOI: 10.7270/Q2WQ03HW
					More data for this Ligand-Target Pair