BDBM50229518 CHEMBL4095053

SMILES: CCC(C)(C)C(=O)N(C)Cc1sccc1C

InChI Key: InChIKey=BVPOXNLFLCCXFZ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229518   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50229518 (CHEMBL4095053) Show SMILES CCC(C)(C)C(=O)N(C)Cc1sccc1C Show InChI InChI=1S/C13H21NOS/c1-6-13(3,4)12(15)14(5)9-11-10(2)7-8-16-11/h7-8H,6,9H2,1-5H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.53E+3	n/a	n/a	n/a	n/a
National Institute of Biological Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1 in human HT-29 cells assessed as reduction in TNFalpha/z-VAD-FMK-induced necrosis after 24 hrs by Cell Titer-Glo luminescent cell ...				J Med Chem 60: 972-986 (2017) BindingDB Entry DOI: 10.7270/Q2QC05QD
					More data for this Ligand-Target Pair