BDBM50229613 ICI-125211::TIOTIDINE::Tiotidine

SMILES: [#6]\[#7]=[#6](\[#7]-[#6]-[#6]-[#16]-[#6]-c1csc(\[#7]=[#6](/[#7])-[#7])n1)-[#7]C#N

InChI Key: InChIKey=YDDXVAXDYKBWDX-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229613   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50229613 (ICI-125211 | TIOTIDINE | Tiotidine) Show SMILES [#6]\[#7]=[#6](\[#7]-[#6]-[#6]-[#16]-[#6]-c1csc(\[#7]=[#6](/[#7])-[#7])n1)-[#7]C#N Show InChI InChI=1S/C10H16N8S2/c1-14-9(16-6-11)15-2-3-19-4-7-5-20-10(17-7)18-8(12)13/h5H,2-4H2,1H3,(H2,14,15,16)(H4,12,13,17,18)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description Inhibition of [125I]APT binding to H2 receptors in guinea pig cerebral membranes.				J Med Chem 35: 2231-8 (1992) BindingDB Entry DOI: 10.7270/Q23T9JFP
					More data for this Ligand-Target Pair