BDBM50229618 CHEMBL23335

SMILES: Cc1ncn(n1)C1CN2CCC1CC2

InChI Key: InChIKey=KRCHFWVMXGGVKG-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50229618   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor (RAT)	BDBM50229618 (CHEMBL23335) Show SMILES Cc1ncn(n1)C1CN2CCC1CC2 |(17.8,-12.62,;17.41,-14.06,;18.48,-15.44,;17.28,-16.78,;15.88,-16.13,;16.04,-14.6,;14.52,-16.91,;14.52,-18.45,;13.19,-19.11,;11.88,-18.45,;11.88,-16.91,;13.19,-16.13,;13.59,-17.62,;12.57,-17.96,)| Show InChI InChI=1S/C10H16N4/c1-8-11-7-14(12-8)10-6-13-4-2-9(10)3-5-13/h7,9-10H,2-6H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibition of [3H]OXO-M binding to Muscarinic receptor from rat cortical homogenates				J Med Chem 35: 1280-90 (1992) BindingDB Entry DOI: 10.7270/Q2G1632Q
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (RAT)	BDBM50229618 (CHEMBL23335) Show SMILES Cc1ncn(n1)C1CN2CCC1CC2 |(17.8,-12.62,;17.41,-14.06,;18.48,-15.44,;17.28,-16.78,;15.88,-16.13,;16.04,-14.6,;14.52,-16.91,;14.52,-18.45,;13.19,-19.11,;11.88,-18.45,;11.88,-16.91,;13.19,-16.13,;13.59,-17.62,;12.57,-17.96,)| Show InChI InChI=1S/C10H16N4/c1-8-11-7-14(12-8)10-6-13-4-2-9(10)3-5-13/h7,9-10H,2-6H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro ability to displace [3H]oxotremorine-M (OXO-M) from rat cerebral cortex muscarinic receptor.				J Med Chem 35: 2392-406 (1992) BindingDB Entry DOI: 10.7270/Q2TF00K5
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (RAT)	BDBM50229618 (CHEMBL23335) Show SMILES Cc1ncn(n1)C1CN2CCC1CC2 |(17.8,-12.62,;17.41,-14.06,;18.48,-15.44,;17.28,-16.78,;15.88,-16.13,;16.04,-14.6,;14.52,-16.91,;14.52,-18.45,;13.19,-19.11,;11.88,-18.45,;11.88,-16.91,;13.19,-16.13,;13.59,-17.62,;12.57,-17.96,)| Show InChI InChI=1S/C10H16N4/c1-8-11-7-14(12-8)10-6-13-4-2-9(10)3-5-13/h7,9-10H,2-6H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro displacement of [3H]quinuclidinyl benzilate (QNB) from rat cerebral cortex muscarinic receptor.				J Med Chem 35: 2392-406 (1992) BindingDB Entry DOI: 10.7270/Q2TF00K5
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (RAT)	BDBM50229618 (CHEMBL23335) Show SMILES Cc1ncn(n1)C1CN2CCC1CC2 |(17.8,-12.62,;17.41,-14.06,;18.48,-15.44,;17.28,-16.78,;15.88,-16.13,;16.04,-14.6,;14.52,-16.91,;14.52,-18.45,;13.19,-19.11,;11.88,-18.45,;11.88,-16.91,;13.19,-16.13,;13.59,-17.62,;12.57,-17.96,)| Show InChI InChI=1S/C10H16N4/c1-8-11-7-14(12-8)10-6-13-4-2-9(10)3-5-13/h7,9-10H,2-6H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibition of [3H]QNB binding to Muscarinic receptor from rat cortical homogenates				J Med Chem 35: 1280-90 (1992) BindingDB Entry DOI: 10.7270/Q2G1632Q
					More data for this Ligand-Target Pair