BDBM50229691 CHEMBL23118

SMILES: Cc1nnn(n1)C1CN2CCC1CC2

InChI Key: InChIKey=VPPCYMOGGLAYBU-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50229691   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor (RAT)	BDBM50229691 (CHEMBL23118) Show SMILES Cc1nnn(n1)C1CN2CCC1CC2 |(18.11,-12.96,;17.7,-14.41,;18.77,-15.8,;17.57,-17.13,;16.17,-16.52,;16.34,-14.95,;14.82,-17.27,;14.82,-18.82,;13.48,-19.48,;12.16,-18.82,;12.16,-17.27,;13.46,-16.5,;13.87,-17.98,;12.85,-18.33,)| Show InChI InChI=1S/C9H15N5/c1-7-10-12-14(11-7)9-6-13-4-2-8(9)3-5-13/h8-9H,2-6H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Compound was tested in vitro for its binding affinity to muscarinic acetylcholine receptor from rat cortical homogenates using [3H]QNB as radioligand				J Med Chem 35: 1280-90 (1992) BindingDB Entry DOI: 10.7270/Q2G1632Q
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (RAT)	BDBM50229691 (CHEMBL23118) Show SMILES Cc1nnn(n1)C1CN2CCC1CC2 |(18.11,-12.96,;17.7,-14.41,;18.77,-15.8,;17.57,-17.13,;16.17,-16.52,;16.34,-14.95,;14.82,-17.27,;14.82,-18.82,;13.48,-19.48,;12.16,-18.82,;12.16,-17.27,;13.46,-16.5,;13.87,-17.98,;12.85,-18.33,)| Show InChI InChI=1S/C9H15N5/c1-7-10-12-14(11-7)9-6-13-4-2-8(9)3-5-13/h8-9H,2-6H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro displacement of [3H]quinuclidinyl benzilate (QNB) from rat cerebral cortex muscarinic receptor.				J Med Chem 35: 2392-406 (1992) BindingDB Entry DOI: 10.7270/Q2TF00K5
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (RAT)	BDBM50229691 (CHEMBL23118) Show SMILES Cc1nnn(n1)C1CN2CCC1CC2 |(18.11,-12.96,;17.7,-14.41,;18.77,-15.8,;17.57,-17.13,;16.17,-16.52,;16.34,-14.95,;14.82,-17.27,;14.82,-18.82,;13.48,-19.48,;12.16,-18.82,;12.16,-17.27,;13.46,-16.5,;13.87,-17.98,;12.85,-18.33,)| Show InChI InChI=1S/C9H15N5/c1-7-10-12-14(11-7)9-6-13-4-2-8(9)3-5-13/h8-9H,2-6H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro ability to displace [3H]oxotremorine-M (OXO-M) from rat cerebral cortex muscarinic receptor.				J Med Chem 35: 2392-406 (1992) BindingDB Entry DOI: 10.7270/Q2TF00K5
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (RAT)	BDBM50229691 (CHEMBL23118) Show SMILES Cc1nnn(n1)C1CN2CCC1CC2 |(18.11,-12.96,;17.7,-14.41,;18.77,-15.8,;17.57,-17.13,;16.17,-16.52,;16.34,-14.95,;14.82,-17.27,;14.82,-18.82,;13.48,-19.48,;12.16,-18.82,;12.16,-17.27,;13.46,-16.5,;13.87,-17.98,;12.85,-18.33,)| Show InChI InChI=1S/C9H15N5/c1-7-10-12-14(11-7)9-6-13-4-2-8(9)3-5-13/h8-9H,2-6H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Compound was tested in vitro for its binding affinity to muscarinic acetylcholine receptor from rat cortical homogenates using [3H]OXO-M as radioliga...				J Med Chem 35: 1280-90 (1992) BindingDB Entry DOI: 10.7270/Q2G1632Q
					More data for this Ligand-Target Pair