BDBM50229891 CHEMBL85288

SMILES: Cc1cc(N)c2cc(NC(=O)\C=C\c3cccc(c3)C(F)(F)F)ccc2n1

InChI Key: InChIKey=CQPFKMRAYQKWEI-VMPITWQZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229891   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C5a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50229891 (CHEMBL85288) Show SMILES Cc1cc(N)c2cc(NC(=O)\C=C\c3cccc(c3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C20H16F3N3O/c1-12-9-17(24)16-11-15(6-7-18(16)25-12)26-19(27)8-5-13-3-2-4-14(10-13)20(21,22)23/h2-11H,1H3,(H2,24,25)(H,26,27)/b8-5+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Ability to inhibit binding of radiolabeled C5a anaphylatoxin to intact membrane bound receptor from human neutrophils.				J Med Chem 35: 252-8 (1992) BindingDB Entry DOI: 10.7270/Q2X63Q54
					More data for this Ligand-Target Pair