BDBM50230178 CHEMBL4087541
SMILES: Nc1ncc2ccc(cc2n1)-c1ccc(NC(=S)Nc2ccc3OCOc3c2)cc1
InChI Key: InChIKey=VXKYLNNGZFWMAC-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Angiopoietin-1 receptor (Homo sapiens (Human)) | BDBM50230178 (CHEMBL4087541) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a |
Xi'an Jiaotong University Curated by ChEMBL | Assay Description Inhibition of TIE-2 (unknown origin) after 60 mins by ADP-Glo assay | Eur J Med Chem 127: 275-285 (2017) BindingDB Entry DOI: 10.7270/Q2XW4N27 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50230178 (CHEMBL4087541) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Xi'an Jiaotong University Curated by ChEMBL | Assay Description Inhibition of VEGFR2 (unknown origin) after 60 mins by ADP-Glo assay | Eur J Med Chem 127: 275-285 (2017) BindingDB Entry DOI: 10.7270/Q2XW4N27 | |||||||||||
More data for this Ligand-Target Pair |