null

SMILES: C[C@H]1CN(C[C@@H](C)O1)[C@@H](CN(c1ccc(Oc2ccc(Cl)cc2)cc1)S(C)(=O)=O)C(=O)NO

InChI Key: InChIKey=USBYYTHGWSZFCH-MRUHUIDDSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50230525   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50230525 ((S)-3-(N-(4-(4-chlorophenoxy)phenyl)methan-2-ylsul...) Show SMILES C[C@H]1CN(C[C@@H](C)O1)[C@@H](CN(c1ccc(Oc2ccc(Cl)cc2)cc1)S(C)(=O)=O)C(=O)NO Show InChI InChI=1S/C22H28ClN3O6S/c1-15-12-25(13-16(2)31-15)21(22(27)24-28)14-26(33(3,29)30)18-6-10-20(11-7-18)32-19-8-4-17(23)5-9-19/h4-11,15-16,21,28H,12-14H2,1-3H3,(H,24,27)/t15-,16+,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP2				Bioorg Med Chem Lett 18: 1140-5 (2008) Article DOI: 10.1016/j.bmcl.2007.11.129 BindingDB Entry DOI: 10.7270/Q2BP02JM
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50230525 ((S)-3-(N-(4-(4-chlorophenoxy)phenyl)methan-2-ylsul...) Show SMILES C[C@H]1CN(C[C@@H](C)O1)[C@@H](CN(c1ccc(Oc2ccc(Cl)cc2)cc1)S(C)(=O)=O)C(=O)NO Show InChI InChI=1S/C22H28ClN3O6S/c1-15-12-25(13-16(2)31-15)21(22(27)24-28)14-26(33(3,29)30)18-6-10-20(11-7-18)32-19-8-4-17(23)5-9-19/h4-11,15-16,21,28H,12-14H2,1-3H3,(H,24,27)/t15-,16+,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP9				Bioorg Med Chem Lett 18: 1140-5 (2008) Article DOI: 10.1016/j.bmcl.2007.11.129 BindingDB Entry DOI: 10.7270/Q2BP02JM
					More data for this Ligand-Target Pair