BDBM50230538 CHEMBL428779::N-benzyl-5-(3,5-dimethylpiperidin-1-ylsulfonyl)-N-ethyl-3-methylbenzofuran-2-carboxamide
SMILES: CCN(Cc1ccccc1)C(=O)c1oc2ccc(cc2c1C)S(=O)(=O)N1CC(C)CC(C)C1
InChI Key: InChIKey=ZNHNBEXEBBBFMB-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50230538 (CHEMBL428779 | N-benzyl-5-(3,5-dimethylpiperidin-1...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 300 | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd Curated by ChEMBL | Assay Description Inverse agonist activity at human CB1 receptor by [35S]GTPgammaS incorporation assay | Bioorg Med Chem Lett 19: 4183-90 (2009) Article DOI: 10.1016/j.bmcl.2009.05.114 BindingDB Entry DOI: 10.7270/Q2XP75VT | |||||||||||
More data for this Ligand-Target Pair |