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SMILES: CC(C)c1c(c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1)S(=O)(=O)N1CCC1

InChI Key: InChIKey=BQXHXGRMRBSNNL-DNQXCXABSA-M

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231037   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
3-hydroxy-3-methylglutaryl-coenzyme A reductase


(Rattus norvegicus (rat))		BDBM50231037
PNG
(CHEMBL253054 | sodium (3R,5R)-7-(3-(azetidin-1-yls...)
Show SMILES CC(C)c1c(c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1)S(=O)(=O)N1CCC1
Show InChI InChI=1S/C29H35FN2O6S/c1-19(2)27-29(39(37,38)31-14-6-15-31)26(20-7-4-3-5-8-20)28(21-9-11-22(30)12-10-21)32(27)16-13-23(33)17-24(34)18-25(35)36/h3-5,7-12,19,23-24,33-34H,6,13-18H2,1-2H3,(H,35,36)/p-1/t23-,24-/m1/s1
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PubMed
n/an/a 1.80n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of rat microsomal HMGCoA reductase

Bioorg Med Chem Lett 18: 1151-6 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.124
BindingDB Entry DOI: 10.7270/Q2TQ6191
More data for this
Ligand-Target Pair