null
SMILES: CC(C)(C)c1ccc(NC(=O)c2ccc(OC(F)(F)F)cc2)cc1
InChI Key: InChIKey=CAYRUALOKFMCPR-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM50231051 (CHEMBL252226 | N-(4-tert-butylphenyl)-4-(trifluoro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research & Development Curated by ChEMBL | Assay Description Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced calcium influx in HEK293 cells | Bioorg Med Chem Lett 18: 1072-8 (2008) Article DOI: 10.1016/j.bmcl.2007.12.007 BindingDB Entry DOI: 10.7270/Q2PZ58K9 | |||||||||||
More data for this Ligand-Target Pair |