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SMILES: Oc1ccc2c(O)ccc(CCNC(=O)c3ccc(OC(F)(F)F)cc3)c2c1

InChI Key: InChIKey=LXNUJHCVLGLBLV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231088   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50231088
PNG
(CHEMBL253624 | N-(2-(4,7-dihydroxynaphthalen-1-yl)...)
Show SMILES Oc1ccc2c(O)ccc(CCNC(=O)c3ccc(OC(F)(F)F)cc3)c2c1
Show InChI InChI=1S/C20H16F3NO4/c21-20(22,23)28-15-5-1-13(2-6-15)19(27)24-10-9-12-3-8-18(26)16-7-4-14(25)11-17(12)16/h1-8,11,25-26H,9-10H2,(H,24,27)
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MMDB

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n/an/a 76n/an/an/an/an/an/a



Pfizer Global Research & Development

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced calcium influx in HEK293 cells

Bioorg Med Chem Lett 18: 1072-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.007
BindingDB Entry DOI: 10.7270/Q2PZ58K9
More data for this
Ligand-Target Pair