BDBM50231831 CHEMBL4086155

SMILES: CN(C)[C@H]1CN(Cc2c(C)cccc2F)C[C@@H]1c1ccc(cc1)N1CCN(CC1)S(=O)(=O)c1cccc(F)c1

InChI Key: InChIKey=OVVCKHWAFREJPO-DGPALRBDSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50231831   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polycomb protein EED (EED) (Homo sapiens (Human))	BDBM50231831 (CHEMBL4086155) Show SMILES CN(C)[C@H]1CN(Cc2c(C)cccc2F)C[C@@H]1c1ccc(cc1)N1CCN(CC1)S(=O)(=O)c1cccc(F)c1 |r| Show InChI InChI=1S/C30H36F2N4O2S/c1-22-6-4-9-29(32)27(22)19-34-20-28(30(21-34)33(2)3)23-10-12-25(13-11-23)35-14-16-36(17-15-35)39(37,38)26-8-5-7-24(31)18-26/h4-13,18,28,30H,14-17,19-21H2,1-3H3/t28-,30+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of pyrrolidine inhibitor-based oregon-green probe binding to GST-tagged EED (unknown origin) after 1 hr by assay explorer integrated Lanth...				ACS Med Chem Lett 8: 461-465 (2017) BindingDB Entry DOI: 10.7270/Q2XS5XM2
					More data for this Ligand-Target Pair
Polycomb protein EED (EED) (Homo sapiens (Human))	BDBM50231831 (CHEMBL4086155) Show SMILES CN(C)[C@H]1CN(Cc2c(C)cccc2F)C[C@@H]1c1ccc(cc1)N1CCN(CC1)S(=O)(=O)c1cccc(F)c1 |r| Show InChI InChI=1S/C30H36F2N4O2S/c1-22-6-4-9-29(32)27(22)19-34-20-28(30(21-34)33(2)3)23-10-12-25(13-11-23)35-14-16-36(17-15-35)39(37,38)26-8-5-7-24(31)18-26/h4-13,18,28,30H,14-17,19-21H2,1-3H3/t28-,30+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of pyrrolidine inhibitor-based oregon-green probe binding to GST-tagged EED (unknown origin) after 1 hr by LanthaScreen TR-FRET assay				ACS Med Chem Lett 8: 461-465 (2017) BindingDB Entry DOI: 10.7270/Q2XS5XM2
					More data for this Ligand-Target Pair