BDBM50231834 CHEMBL4059817

SMILES: CN(C)[C@H]1CN(Cc2c(C)cccc2F)C[C@@H]1c1ccc(cc1)N1CCC(CC1)NC(C)=O

InChI Key: InChIKey=DBWWMSJPXUQEBS-VPUSJEBWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50231834   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polycomb protein EED (Homo sapiens (Human))	BDBM50231834 (CHEMBL4059817) Show SMILES CN(C)[C@H]1CN(Cc2c(C)cccc2F)C[C@@H]1c1ccc(cc1)N1CCC(CC1)NC(C)=O |r| Show InChI InChI=1S/C27H37FN4O/c1-19-6-5-7-26(28)24(19)16-31-17-25(27(18-31)30(3)4)21-8-10-23(11-9-21)32-14-12-22(13-15-32)29-20(2)33/h5-11,22,25,27H,12-18H2,1-4H3,(H,29,33)/t25-,27+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of pyrrolidine inhibitor-based oregon-green probe binding to GST-tagged EED (unknown origin) after 1 hr by assay explorer integrated Lanth...				ACS Med Chem Lett 8: 461-465 (2017) BindingDB Entry DOI: 10.7270/Q2XS5XM2
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50231834 (CHEMBL4059817) Show SMILES CN(C)[C@H]1CN(Cc2c(C)cccc2F)C[C@@H]1c1ccc(cc1)N1CCC(CC1)NC(C)=O |r| Show InChI InChI=1S/C27H37FN4O/c1-19-6-5-7-26(28)24(19)16-31-17-25(27(18-31)30(3)4)21-8-10-23(11-9-21)32-14-12-22(13-15-32)29-20(2)33/h5-11,22,25,27H,12-18H2,1-4H3,(H,29,33)/t25-,27+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of pyrrolidine inhibitor-based oregon-green probe binding to GST-tagged EED (unknown origin) after 1 hr by LanthaScreen TR-FRET assay				ACS Med Chem Lett 8: 461-465 (2017) BindingDB Entry DOI: 10.7270/Q2XS5XM2
					More data for this Ligand-Target Pair