BDBM50231841 CHEMBL4093192

SMILES: CN(C)[C@H]1CN(Cc2c(C)cccc2F)C[C@@H]1c1ccc(cc1)N1CCN(CC1)C(=O)N1CCCC1

InChI Key: InChIKey=FOMPUZFBUQIWRP-IAPPQJPRSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50231841   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polycomb protein EED (EED) (Homo sapiens (Human))	BDBM50231841 (CHEMBL4093192) Show SMILES CN(C)[C@H]1CN(Cc2c(C)cccc2F)C[C@@H]1c1ccc(cc1)N1CCN(CC1)C(=O)N1CCCC1 |r| Show InChI InChI=1S/C29H40FN5O/c1-22-7-6-8-27(30)25(22)19-32-20-26(28(21-32)31(2)3)23-9-11-24(12-10-23)33-15-17-35(18-16-33)29(36)34-13-4-5-14-34/h6-12,26,28H,4-5,13-21H2,1-3H3/t26-,28+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of pyrrolidine inhibitor-based oregon-green probe binding to GST-tagged EED (unknown origin) after 1 hr by assay explorer integrated Lanth...				ACS Med Chem Lett 8: 461-465 (2017) BindingDB Entry DOI: 10.7270/Q2XS5XM2
					More data for this Ligand-Target Pair
Polycomb protein EED (EED) (Homo sapiens (Human))	BDBM50231841 (CHEMBL4093192) Show SMILES CN(C)[C@H]1CN(Cc2c(C)cccc2F)C[C@@H]1c1ccc(cc1)N1CCN(CC1)C(=O)N1CCCC1 |r| Show InChI InChI=1S/C29H40FN5O/c1-22-7-6-8-27(30)25(22)19-32-20-26(28(21-32)31(2)3)23-9-11-24(12-10-23)33-15-17-35(18-16-33)29(36)34-13-4-5-14-34/h6-12,26,28H,4-5,13-21H2,1-3H3/t26-,28+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of pyrrolidine inhibitor-based oregon-green probe binding to GST-tagged EED (unknown origin) after 1 hr by LanthaScreen TR-FRET assay				ACS Med Chem Lett 8: 461-465 (2017) BindingDB Entry DOI: 10.7270/Q2XS5XM2
					More data for this Ligand-Target Pair