BDBM50231863 CHEMBL4066590

SMILES: CN(C)[C@H]1CN(Cc2c(C)cccc2F)C[C@@H]1c1ccc(cc1)N1CCC2(CNC(=O)O2)CC1

InChI Key: InChIKey=QWNVXJNNZSGENC-NOZRDPDXSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50231863   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polycomb protein EED (EED) (Homo sapiens (Human))	BDBM50231863 (CHEMBL4066590) Show SMILES CN(C)[C@H]1CN(Cc2c(C)cccc2F)C[C@@H]1c1ccc(cc1)N1CCC2(CNC(=O)O2)CC1 |r| Show InChI InChI=1S/C27H35FN4O2/c1-19-5-4-6-24(28)22(19)15-31-16-23(25(17-31)30(2)3)20-7-9-21(10-8-20)32-13-11-27(12-14-32)18-29-26(33)34-27/h4-10,23,25H,11-18H2,1-3H3,(H,29,33)/t23-,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of pyrrolidine inhibitor-based oregon-green probe binding to GST-tagged EED (unknown origin) after 1 hr by assay explorer integrated Lanth...				ACS Med Chem Lett 8: 461-465 (2017) BindingDB Entry DOI: 10.7270/Q2XS5XM2
					More data for this Ligand-Target Pair
Polycomb protein EED (EED) (Homo sapiens (Human))	BDBM50231863 (CHEMBL4066590) Show SMILES CN(C)[C@H]1CN(Cc2c(C)cccc2F)C[C@@H]1c1ccc(cc1)N1CCC2(CNC(=O)O2)CC1 |r| Show InChI InChI=1S/C27H35FN4O2/c1-19-5-4-6-24(28)22(19)15-31-16-23(25(17-31)30(2)3)20-7-9-21(10-8-20)32-13-11-27(12-14-32)18-29-26(33)34-27/h4-10,23,25H,11-18H2,1-3H3,(H,29,33)/t23-,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of pyrrolidine inhibitor-based oregon-green probe binding to GST-tagged EED (unknown origin) after 1 hr by LanthaScreen TR-FRET assay				ACS Med Chem Lett 8: 461-465 (2017) BindingDB Entry DOI: 10.7270/Q2XS5XM2
					More data for this Ligand-Target Pair