BDBM50231877 CHEMBL4064647

SMILES: COC(=O)N1CCN(CC1)c1ccc(cc1)[C@H]1CN(Cc2c(C)cccc2F)C[C@@H]1N(C)C

InChI Key: InChIKey=DBYZYINLMCHTES-NOZRDPDXSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50231877   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polycomb protein EED (Homo sapiens (Human))	BDBM50231877 (CHEMBL4064647) Show SMILES COC(=O)N1CCN(CC1)c1ccc(cc1)[C@H]1CN(Cc2c(C)cccc2F)C[C@@H]1N(C)C |r| Show InChI InChI=1S/C26H35FN4O2/c1-19-6-5-7-24(27)22(19)16-29-17-23(25(18-29)28(2)3)20-8-10-21(11-9-20)30-12-14-31(15-13-30)26(32)33-4/h5-11,23,25H,12-18H2,1-4H3/t23-,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of pyrrolidine inhibitor-based oregon-green probe binding to GST-tagged EED (unknown origin) after 1 hr by LanthaScreen TR-FRET assay				ACS Med Chem Lett 8: 461-465 (2017) BindingDB Entry DOI: 10.7270/Q2XS5XM2
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50231877 (CHEMBL4064647) Show SMILES COC(=O)N1CCN(CC1)c1ccc(cc1)[C@H]1CN(Cc2c(C)cccc2F)C[C@@H]1N(C)C |r| Show InChI InChI=1S/C26H35FN4O2/c1-19-6-5-7-24(27)22(19)16-29-17-23(25(18-29)28(2)3)20-8-10-21(11-9-20)30-12-14-31(15-13-30)26(32)33-4/h5-11,23,25H,12-18H2,1-4H3/t23-,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of pyrrolidine inhibitor-based oregon-green probe binding to GST-tagged EED (unknown origin) after 1 hr by assay explorer integrated Lanth...				ACS Med Chem Lett 8: 461-465 (2017) BindingDB Entry DOI: 10.7270/Q2XS5XM2
					More data for this Ligand-Target Pair