null

SMILES: C[C@@H](NC(=O)c1cc(cc(c1)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)CNCc1ccc2cc[nH]c2c1)N(C)S(C)(=O)=O)c1ccccc1

InChI Key: InChIKey=SMQRADVWSPEEOF-XOUBVTBXSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50231933   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM50231933 (CHEMBL253929 | N1-((2S,3R)-4-((1H-indol-6-yl)methy...) Show SMILES C[C@@H](NC(=O)c1cc(cc(c1)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)CNCc1ccc2cc[nH]c2c1)N(C)S(C)(=O)=O)c1ccccc1 Show InChI InChI=1S/C37H41N5O5S/c1-25(28-12-8-5-9-13-28)40-36(44)30-20-31(22-32(21-30)42(2)48(3,46)47)37(45)41-34(18-26-10-6-4-7-11-26)35(43)24-38-23-27-14-15-29-16-17-39-33(29)19-27/h4-17,19-22,25,34-35,38-39,43H,18,23-24H2,1-3H3,(H,40,44)(H,41,45)/t25-,34+,35-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity to recombinant memapsin 2				Bioorg Med Chem Lett 18: 1031-6 (2008) Article DOI: 10.1016/j.bmcl.2007.12.028 BindingDB Entry DOI: 10.7270/Q2513XZC
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM50231933 (CHEMBL253929 | N1-((2S,3R)-4-((1H-indol-6-yl)methy...) Show SMILES C[C@@H](NC(=O)c1cc(cc(c1)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)CNCc1ccc2cc[nH]c2c1)N(C)S(C)(=O)=O)c1ccccc1 Show InChI InChI=1S/C37H41N5O5S/c1-25(28-12-8-5-9-13-28)40-36(44)30-20-31(22-32(21-30)42(2)48(3,46)47)37(45)41-34(18-26-10-6-4-7-11-26)35(43)24-38-23-27-14-15-29-16-17-39-33(29)19-27/h4-17,19-22,25,34-35,38-39,43H,18,23-24H2,1-3H3,(H,40,44)(H,41,45)/t25-,34+,35-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of memapsin 2 expressed in CHO cells				Bioorg Med Chem Lett 18: 1031-6 (2008) Article DOI: 10.1016/j.bmcl.2007.12.028 BindingDB Entry DOI: 10.7270/Q2513XZC
					More data for this Ligand-Target Pair