null
SMILES: COC1=CC(=O)C(=O)C(CCCCCCCCCCCO)=C1OC
InChI Key: InChIKey=MBKSIONPOPLZQQ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50232002 (CHEMBL4095644) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Second University of Naples Curated by ChEMBL | Assay Description Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of A23187-induced product formation using arachidonic acid as substrate prei... | Eur J Med Chem 127: 715-726 (2017) BindingDB Entry DOI: 10.7270/Q2DR2XQ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50232002 (CHEMBL4095644) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.96E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Second University of Naples Curated by ChEMBL | Assay Description Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins follow... | Eur J Med Chem 127: 715-726 (2017) BindingDB Entry DOI: 10.7270/Q2DR2XQ8 | |||||||||||
More data for this Ligand-Target Pair |