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SMILES: CC(C)(C)c1ccc2CC(Cc2c1)NC(=O)Nc1cccc2[nH]ncc12

InChI Key: InChIKey=JMWSQSYRBYDBND-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50232112   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50232112
PNG
(1-(5-tert-butyl-2,3-dihydro-1H-inden-2-yl)-3-(1H-i...)
Show SMILES CC(C)(C)c1ccc2CC(Cc2c1)NC(=O)Nc1cccc2[nH]ncc12 |w:9.14|
Show InChI InChI=1S/C21H24N4O/c1-21(2,3)15-8-7-13-10-16(11-14(13)9-15)23-20(26)24-18-5-4-6-19-17(18)12-22-25-19/h4-9,12,16H,10-11H2,1-3H3,(H,22,25)(H2,23,24,26)
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n/an/a 10n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Blockade of human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux

J Med Chem 51: 392-5 (2008)


Article DOI: 10.1021/jm701007g
BindingDB Entry DOI: 10.7270/Q218367F
More data for this
Ligand-Target Pair