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SMILES: FC(F)(F)C1CCN(CC1)c1cccc2C(CCc12)NC(=O)Nc1cccc2[nH]ncc12

InChI Key: InChIKey=TZTRDENRXZLOMH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50232125   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50232125
PNG
(1-(1H-Indazol-4-yl)-3-[4-(4-trifluoromethyl)piperi...)
Show SMILES FC(F)(F)C1CCN(CC1)c1cccc2C(CCc12)NC(=O)Nc1cccc2[nH]ncc12 |w:15.21|
Show InChI InChI=1S/C23H24F3N5O/c24-23(25,26)14-9-11-31(12-10-14)21-6-1-3-15-16(21)7-8-19(15)29-22(32)28-18-4-2-5-20-17(18)13-27-30-20/h1-6,13-14,19H,7-12H2,(H,27,30)(H2,28,29,32)
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n/an/a 7n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Blockade of human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux

J Med Chem 51: 392-5 (2008)


Article DOI: 10.1021/jm701007g
BindingDB Entry DOI: 10.7270/Q218367F
More data for this
Ligand-Target Pair