BDBM50232237 4-(2-chlorophenyl)-9-hydroxy-6-methyl-8-(4-morpholinobutyl)pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::CHEMBL438566

SMILES: Cn1c2cc(CCCCN3CCOCC3)c(O)cc2c2c3C(=O)NC(=O)c3c(cc12)-c1ccccc1Cl

InChI Key: InChIKey=ZPHXRUNWRGJFDV-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50232237   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50232237 (4-(2-chlorophenyl)-9-hydroxy-6-methyl-8-(4-morphol...) Show SMILES Cn1c2cc(CCCCN3CCOCC3)c(O)cc2c2c3C(=O)NC(=O)c3c(cc12)-c1ccccc1Cl Show InChI InChI=1S/C29H28ClN3O4/c1-32-22-14-17(6-4-5-9-33-10-12-37-13-11-33)24(34)16-20(22)25-23(32)15-19(18-7-2-3-8-21(18)30)26-27(25)29(36)31-28(26)35/h2-3,7-8,14-16,34H,4-6,9-13H2,1H3,(H,31,35,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of Chk1				Bioorg Med Chem Lett 18: 929-33 (2008) Article DOI: 10.1016/j.bmcl.2007.12.046 BindingDB Entry DOI: 10.7270/Q2ZS2XC3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase WEE1 (Homo sapiens (Human))	BDBM50232237 (4-(2-chlorophenyl)-9-hydroxy-6-methyl-8-(4-morphol...) Show SMILES Cn1c2cc(CCCCN3CCOCC3)c(O)cc2c2c3C(=O)NC(=O)c3c(cc12)-c1ccccc1Cl Show InChI InChI=1S/C29H28ClN3O4/c1-32-22-14-17(6-4-5-9-33-10-12-37-13-11-33)24(34)16-20(22)25-23(32)15-19(18-7-2-3-8-21(18)30)26-27(25)29(36)31-28(26)35/h2-3,7-8,14-16,34H,4-6,9-13H2,1H3,(H,31,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of human Wee1				Bioorg Med Chem Lett 18: 929-33 (2008) Article DOI: 10.1016/j.bmcl.2007.12.046 BindingDB Entry DOI: 10.7270/Q2ZS2XC3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase WEE1 (Homo sapiens (Human))	BDBM50232237 (4-(2-chlorophenyl)-9-hydroxy-6-methyl-8-(4-morphol...) Show SMILES Cn1c2cc(CCCCN3CCOCC3)c(O)cc2c2c3C(=O)NC(=O)c3c(cc12)-c1ccccc1Cl Show InChI InChI=1S/C29H28ClN3O4/c1-32-22-14-17(6-4-5-9-33-10-12-37-13-11-33)24(34)16-20(22)25-23(32)15-19(18-7-2-3-8-21(18)30)26-27(25)29(36)31-28(26)35/h2-3,7-8,14-16,34H,4-6,9-13H2,1H3,(H,31,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Chulalongkorn University Curated by ChEMBL					Assay Description Inhibition of human Wee1				Eur J Med Chem 44: 1383-95 (2009) Article DOI: 10.1016/j.ejmech.2008.09.027 BindingDB Entry DOI: 10.7270/Q2X34XB6
					More data for this Ligand-Target Pair