BDBM50232351 CHEMBL4100664

SMILES: CN(C)Cc1c(C)n(Cc2ccc(cc2)C(=O)NO)c2ccccc12

InChI Key: InChIKey=AWFYSKUENHXUOS-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50232351   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50232351 (CHEMBL4100664) Show SMILES CN(C)Cc1c(C)n(Cc2ccc(cc2)C(=O)NO)c2ccccc12 Show InChI InChI=1S/C20H23N3O2/c1-14-18(13-22(2)3)17-6-4-5-7-19(17)23(14)12-15-8-10-16(11-9-15)20(24)21-25/h4-11,25H,12-13H2,1-3H3,(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
Taipei Medical University Curated by ChEMBL					Assay Description Inhibition of full length human recombinant C-terminal FLAG-His-tagged HDAC1 expressed in Sf21 cells using RHKK(Ac) as substrate after 60 mins by flu...				Eur J Med Chem 127: 115-127 (2017) BindingDB Entry DOI: 10.7270/Q20K2BT4
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50232351 (CHEMBL4100664) Show SMILES CN(C)Cc1c(C)n(Cc2ccc(cc2)C(=O)NO)c2ccccc12 Show InChI InChI=1S/C20H23N3O2/c1-14-18(13-22(2)3)17-6-4-5-7-19(17)23(14)12-15-8-10-16(11-9-15)20(24)21-25/h4-11,25H,12-13H2,1-3H3,(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Taipei Medical University Curated by ChEMBL					Assay Description Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in Sf9 cells using RHKK(Ac) as substrate after 90 mins by fluorimet...				Eur J Med Chem 127: 115-127 (2017) BindingDB Entry DOI: 10.7270/Q20K2BT4
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50232351 (CHEMBL4100664) Show SMILES CN(C)Cc1c(C)n(Cc2ccc(cc2)C(=O)NO)c2ccccc12 Show InChI InChI=1S/C20H23N3O2/c1-14-18(13-22(2)3)17-6-4-5-7-19(17)23(14)12-15-8-10-16(11-9-15)20(24)21-25/h4-11,25H,12-13H2,1-3H3,(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
Taipei Medical University Curated by ChEMBL					Assay Description Inhibition of full length human recombinant C-terminal GST-tagged HDAC2 expressed in insect cells using RHKK(Ac) as substrate after 60 mins by fluori...				Eur J Med Chem 127: 115-127 (2017) BindingDB Entry DOI: 10.7270/Q20K2BT4
					More data for this Ligand-Target Pair