BDBM50232360 CHEMBL4104572

SMILES: CN(C)C(=O)c1cn(c2ccccc12)S(=O)(=O)c1ccc(\C=C\C(=O)NO)cc1

InChI Key: InChIKey=OUKAWAWYISJJLW-FMIVXFBMSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50232360   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50232360 (CHEMBL4104572) Show SMILES CN(C)C(=O)c1cn(c2ccccc12)S(=O)(=O)c1ccc(\C=C\C(=O)NO)cc1 Show InChI InChI=1S/C20H19N3O5S/c1-22(2)20(25)17-13-23(18-6-4-3-5-16(17)18)29(27,28)15-10-7-14(8-11-15)9-12-19(24)21-26/h3-13,26H,1-2H3,(H,21,24)/b12-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Taipei Medical University Curated by ChEMBL					Assay Description Inhibition of full length human recombinant C-terminal FLAG-His-tagged HDAC1 expressed in Sf21 cells using RHKK(Ac) as substrate after 60 mins by flu...				Eur J Med Chem 127: 115-127 (2017) BindingDB Entry DOI: 10.7270/Q20K2BT4
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50232360 (CHEMBL4104572) Show SMILES CN(C)C(=O)c1cn(c2ccccc12)S(=O)(=O)c1ccc(\C=C\C(=O)NO)cc1 Show InChI InChI=1S/C20H19N3O5S/c1-22(2)20(25)17-13-23(18-6-4-3-5-16(17)18)29(27,28)15-10-7-14(8-11-15)9-12-19(24)21-26/h3-13,26H,1-2H3,(H,21,24)/b12-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Taipei Medical University Curated by ChEMBL					Assay Description Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in Sf9 cells using RHKK(Ac) as substrate after 90 mins by fluorimet...				Eur J Med Chem 127: 115-127 (2017) BindingDB Entry DOI: 10.7270/Q20K2BT4
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50232360 (CHEMBL4104572) Show SMILES CN(C)C(=O)c1cn(c2ccccc12)S(=O)(=O)c1ccc(\C=C\C(=O)NO)cc1 Show InChI InChI=1S/C20H19N3O5S/c1-22(2)20(25)17-13-23(18-6-4-3-5-16(17)18)29(27,28)15-10-7-14(8-11-15)9-12-19(24)21-26/h3-13,26H,1-2H3,(H,21,24)/b12-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Taipei Medical University Curated by ChEMBL					Assay Description Inhibition of full length human recombinant C-terminal GST-tagged HDAC2 expressed in insect cells using RHKK(Ac) as substrate after 60 mins by fluori...				Eur J Med Chem 127: 115-127 (2017) BindingDB Entry DOI: 10.7270/Q20K2BT4
					More data for this Ligand-Target Pair