BDBM50232362 CHEMBL4079799

SMILES: CN(C)Cc1c(C)n(Cc2ccc(\C=C\C(=O)NO)cc2)c2ccccc12

InChI Key: InChIKey=TXULANXUEGXDJS-OUKQBFOZSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50232362   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50232362 (CHEMBL4079799) Show SMILES CN(C)Cc1c(C)n(Cc2ccc(\C=C\C(=O)NO)cc2)c2ccccc12 Show InChI InChI=1S/C22H25N3O2/c1-16-20(15-24(2)3)19-6-4-5-7-21(19)25(16)14-18-10-8-17(9-11-18)12-13-22(26)23-27/h4-13,27H,14-15H2,1-3H3,(H,23,26)/b13-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Taipei Medical University Curated by ChEMBL					Assay Description Inhibition of full length human recombinant C-terminal GST-tagged HDAC2 expressed in insect cells using RHKK(Ac) as substrate after 60 mins by fluori...				Eur J Med Chem 127: 115-127 (2017) BindingDB Entry DOI: 10.7270/Q20K2BT4
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50232362 (CHEMBL4079799) Show SMILES CN(C)Cc1c(C)n(Cc2ccc(\C=C\C(=O)NO)cc2)c2ccccc12 Show InChI InChI=1S/C22H25N3O2/c1-16-20(15-24(2)3)19-6-4-5-7-21(19)25(16)14-18-10-8-17(9-11-18)12-13-22(26)23-27/h4-13,27H,14-15H2,1-3H3,(H,23,26)/b13-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Taipei Medical University Curated by ChEMBL					Assay Description Inhibition of full length human recombinant C-terminal FLAG-His-tagged HDAC1 expressed in Sf21 cells using RHKK(Ac) as substrate after 60 mins by flu...				Eur J Med Chem 127: 115-127 (2017) BindingDB Entry DOI: 10.7270/Q20K2BT4
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50232362 (CHEMBL4079799) Show SMILES CN(C)Cc1c(C)n(Cc2ccc(\C=C\C(=O)NO)cc2)c2ccccc12 Show InChI InChI=1S/C22H25N3O2/c1-16-20(15-24(2)3)19-6-4-5-7-21(19)25(16)14-18-10-8-17(9-11-18)12-13-22(26)23-27/h4-13,27H,14-15H2,1-3H3,(H,23,26)/b13-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.60	n/a	n/a	n/a	n/a	n/a	n/a
Taipei Medical University Curated by ChEMBL					Assay Description Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in Sf9 cells using RHKK(Ac) as substrate after 90 mins by fluorimet...				Eur J Med Chem 127: 115-127 (2017) BindingDB Entry DOI: 10.7270/Q20K2BT4
					More data for this Ligand-Target Pair