BDBM50232460 CHEMBL4101860

SMILES: c1ccc(\N=N/c2ccc(cc2)C#Cc2ccccn2)nc1

InChI Key: InChIKey=CWAVNLYIGIXETP-DQRAZIAOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50232460   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50232460 (CHEMBL4101860) Show SMILES c1ccc(\N=N/c2ccc(cc2)C#Cc2ccccn2)nc1 Show InChI InChI=1S/C18H12N4/c1-3-13-19-16(5-1)10-7-15-8-11-17(12-9-15)21-22-18-6-2-4-14-20-18/h1-6,8-9,11-14H/b22-21-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC) Curated by ChEMBL					Assay Description Negative allosteric modulation of rat N-terminal HA-tagged mGlu5 receptor expressed in HEK293 cells co-expressing N-terminal HA-tagged EAAC1 assessed...				Eur J Med Chem 127: 567-576 (2017) BindingDB Entry DOI: 10.7270/Q2736T4T
					More data for this Ligand-Target Pair