BDBM50232550 CHEMBL4062620

SMILES: C[C@H](NC(=O)c1cc(Cl)cnc1Oc1cccc(Cl)c1)c1ccc(cc1)C(O)=O

InChI Key: InChIKey=PAASJZUYDQEILO-LBPRGKRZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50232550   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50232550 (CHEMBL4062620) Show SMILES C[C@H](NC(=O)c1cc(Cl)cnc1Oc1cccc(Cl)c1)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C21H16Cl2N2O4/c1-12(13-5-7-14(8-6-13)21(27)28)25-19(26)18-10-16(23)11-24-20(18)29-17-4-2-3-15(22)9-17/h2-12H,1H3,(H,25,26)(H,27,28)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
AskAt Inc. Curated by ChEMBL					Assay Description Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assay				Bioorg Med Chem Lett 27: 1186-1192 (2017) BindingDB Entry DOI: 10.7270/Q2Q242F0
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50232550 (CHEMBL4062620) Show SMILES C[C@H](NC(=O)c1cc(Cl)cnc1Oc1cccc(Cl)c1)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C21H16Cl2N2O4/c1-12(13-5-7-14(8-6-13)21(27)28)25-19(26)18-10-16(23)11-24-20(18)29-17-4-2-3-15(22)9-17/h2-12H,1H3,(H,25,26)(H,27,28)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
AskAt Inc. Curated by ChEMBL					Assay Description Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assay				Bioorg Med Chem Lett 27: 1186-1192 (2017) BindingDB Entry DOI: 10.7270/Q2Q242F0
					More data for this Ligand-Target Pair