BDBM50232723 4-(pyridin-4-yl)-3-o-tolylquinolin-2(1H)-one::CHEMBL253852

SMILES: Cc1ccccc1-c1c(-c2ccncc2)c2ccccc2[nH]c1=O

InChI Key: InChIKey=MGQQSPMZALACBL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50232723   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50232723 (4-(pyridin-4-yl)-3-o-tolylquinolin-2(1H)-one | CHE...) Show SMILES Cc1ccccc1-c1c(-c2ccncc2)c2ccccc2[nH]c1=O |(1.24,-15.15,;-.1,-14.38,;-.1,-12.84,;-1.44,-12.08,;-2.78,-12.87,;-2.76,-14.4,;-1.43,-15.16,;-1.42,-16.7,;-2.74,-17.47,;-4.07,-16.7,;-5.41,-17.47,;-6.75,-16.7,;-6.74,-15.16,;-5.41,-14.38,;-4.08,-15.15,;-2.74,-19.01,;-4.06,-19.78,;-4.06,-21.31,;-2.72,-22.08,;-1.4,-21.31,;-1.41,-19.78,;-.07,-19.01,;-.08,-17.46,;1.25,-16.68,)| Show InChI InChI=1S/C21H16N2O/c1-14-6-2-3-7-16(14)20-19(15-10-12-22-13-11-15)17-8-4-5-9-18(17)23-21(20)24/h2-13H,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha				Bioorg Med Chem Lett 18: 1431-5 (2008) Article DOI: 10.1016/j.bmcl.2007.12.073 BindingDB Entry DOI: 10.7270/Q208652M
					More data for this Ligand-Target Pair