BDBM50233194 CHEMBL4087100

SMILES: CN(C1=CC(=O)C(=O)c2ccccc12)c1ccc(Cl)cc1

InChI Key: InChIKey=WKDORXZSFRPHFF-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50233194   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA: cholesterol acyltransferase (ACAT) (Homo sapiens (Human))	BDBM50233194 (CHEMBL4087100) Show SMILES CN(C1=CC(=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 |t:2| Show InChI InChI=1S/C17H12ClNO2/c1-19(12-8-6-11(18)7-9-12)15-10-16(20)17(21)14-5-3-2-4-13(14)15/h2-10H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of human liver CES1 expressed in baculovirus infected sf9 cells using oseltamivir as substrate				J Med Chem 60: 1568-1579 (2017) BindingDB Entry DOI: 10.7270/Q2FF3VMP
					More data for this Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase (Homo sapiens (Human))	BDBM50233194 (CHEMBL4087100) Show SMILES CN(C1=CC(=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 |t:2| Show InChI InChI=1S/C17H12ClNO2/c1-19(12-8-6-11(18)7-9-12)15-10-16(20)17(21)14-5-3-2-4-13(14)15/h2-10H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of human liver CES1 expressed in baculovirus infected sf9 cells using o-nitrophenyl acetate as substrate monitored at 15 secs interval for...				J Med Chem 60: 1568-1579 (2017) BindingDB Entry DOI: 10.7270/Q2FF3VMP
					More data for this Ligand-Target Pair