BDBM50233223 CHEMBL4060338

SMILES: CCCCCCCCCC[C@@H]1C[C@]2(CCCO2)NC(=N)N1

InChI Key: InChIKey=NODTXKHXBIVQCH-NVXWUHKLSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50233223   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 2 alpha subunit (Homo sapiens (Human))	BDBM50233223 (CHEMBL4060338) Show SMILES CCCCCCCCCC[C@@H]1C[C@]2(CCCO2)NC(=N)N1 |r| Show InChI InChI=1S/C17H33N3O/c1-2-3-4-5-6-7-8-9-11-15-14-17(12-10-13-21-17)20-16(18)19-15/h15H,2-14H2,1H3,(H3,18,19,20)/t15-,17-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.450	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku University Curated by ChEMBL					Assay Description Antagonist activity at human Nav1.2 expressed in HEK293T cells assessed as inhibition of VTD-induced sustained current by whole cell patch clamp meth...				Bioorg Med Chem Lett 27: 1247-1251 (2017) BindingDB Entry DOI: 10.7270/Q2XG9TC3
					More data for this Ligand-Target Pair
Sodium channel protein type 2 alpha subunit (Homo sapiens (Human))	BDBM50233223 (CHEMBL4060338) Show SMILES CCCCCCCCCC[C@@H]1C[C@]2(CCCO2)NC(=N)N1 |r| Show InChI InChI=1S/C17H33N3O/c1-2-3-4-5-6-7-8-9-11-15-14-17(12-10-13-21-17)20-16(18)19-15/h15H,2-14H2,1H3,(H3,18,19,20)/t15-,17-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Tohoku University Curated by ChEMBL					Assay Description Inhibition of Nav1.2 (unknown origin) by cell based assay				Bioorg Med Chem Lett 27: 1247-1251 (2017) BindingDB Entry DOI: 10.7270/Q2XG9TC3
					More data for this Ligand-Target Pair
Sodium channel protein type 2 alpha subunit (Homo sapiens (Human))	BDBM50233223 (CHEMBL4060338) Show SMILES CCCCCCCCCC[C@@H]1C[C@]2(CCCO2)NC(=N)N1 |r| Show InChI InChI=1S/C17H33N3O/c1-2-3-4-5-6-7-8-9-11-15-14-17(12-10-13-21-17)20-16(18)19-15/h15H,2-14H2,1H3,(H3,18,19,20)/t15-,17-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku University Curated by ChEMBL					Assay Description Antagonist activity at human Nav1.2 expressed in HEK293T cells assessed as inhibition of VTD-induced tail current by whole cell patch clamp method re...				Bioorg Med Chem Lett 27: 1247-1251 (2017) BindingDB Entry DOI: 10.7270/Q2XG9TC3
					More data for this Ligand-Target Pair