BDBM50233575 5-(1-(2-(3-(dimethylcarbamoyl)-2-hydroxyphenylamino)-3,4-dioxocyclobut-1-enylamino)propyl)-N,N-dimethylfuran-2-carboxamide::CHEMBL253255

SMILES: CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(o1)C(=O)N(C)C

InChI Key: InChIKey=PHXRSGRVCIOASS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50233575   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50233575 (5-(1-(2-(3-(dimethylcarbamoyl)-2-hydroxyphenylamin...) Show SMILES CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(o1)C(=O)N(C)C |w:2.2| Show InChI InChI=1S/C23H26N4O6/c1-6-13(15-10-11-16(33-15)23(32)27(4)5)24-17-18(21(30)20(17)29)25-14-9-7-8-12(19(14)28)22(31)26(2)3/h7-11,13,24-25,28H,6H2,1-5H3	PDB Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	171	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of CXCR2				Bioorg Med Chem Lett 18: 1318-22 (2008) Article DOI: 10.1016/j.bmcl.2008.01.024 BindingDB Entry DOI: 10.7270/Q2PV6K33
					More data for this Ligand-Target Pair