BDBM50233622 CHEMBL4073011::US10882838, Example 1.35
SMILES: [H][C@@]12CC(C)=CC[C@@]1([H])C(C)(C)Oc1cc(cc(O)c21)C(C)(C)C(=O)OCC
InChI Key: InChIKey=JSXWUVARLKOUGN-HZPDHXFCSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cannabinoid receptor 2 (MOUSE) | BDBM50233622 (CHEMBL4073011 | US10882838, Example 1.35) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in HEK293 cells by scintillation counting method | J Med Chem 58: 665-81 (2015) BindingDB Entry DOI: 10.7270/Q2K076HR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor (MOUSE) | BDBM50233622 (CHEMBL4073011 | US10882838, Example 1.35) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NORTHEASTERN UNIVERSITY US Patent | Assay Description All the cannabinoids discussed in this invention are tested for their ability to bind to CB1 and CB2 receptors using membranes from rat brain or HEK2... | US Patent US10882838 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50233622 (CHEMBL4073011 | US10882838, Example 1.35) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Displacement of [3H]CP-55,940 from human CB2 receptor expressed in HEK293 cells by scintillation counting method | J Med Chem 58: 665-81 (2015) BindingDB Entry DOI: 10.7270/Q2K076HR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50233622 (CHEMBL4073011 | US10882838, Example 1.35) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NORTHEASTERN UNIVERSITY US Patent | Assay Description All the cannabinoids discussed in this invention are tested for their ability to bind to CB1 and CB2 receptors using membranes from rat brain or HEK2... | US Patent US10882838 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM50233622 (CHEMBL4073011 | US10882838, Example 1.35) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Displacement of [3H]CP-55,940 from CB1 receptor in rat brain membranes by scintillation counting method | J Med Chem 58: 665-81 (2015) BindingDB Entry DOI: 10.7270/Q2K076HR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor (Rattus norvegicus (rat)) | BDBM50233622 (CHEMBL4073011 | US10882838, Example 1.35) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NORTHEASTERN UNIVERSITY US Patent | Assay Description All the cannabinoids discussed in this invention are tested for their ability to bind to CB1 and CB2 receptors using membranes from rat brain or HEK2... | US Patent US10882838 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM50233622 (CHEMBL4073011 | US10882838, Example 1.35) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Agonist activity at CB1 receptor in rat brain membranes assessed as reduction in forskolin-stimulated cAMP level measured from 3 data points after 30... | J Med Chem 58: 665-81 (2015) BindingDB Entry DOI: 10.7270/Q2K076HR | |||||||||||
More data for this Ligand-Target Pair |