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SMILES: CSc1sc(cc1S(=O)(=O)c1cccc(c1)-c1ccccc1)C(N)=N

InChI Key: InChIKey=YUIOPWUQMKXINJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50233675   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Complement C1s subcomponent


(Homo sapiens (Human))		BDBM50233675
PNG
(4-(biphenyl-3-sulfonyl)-5-methylsulfanyl-thiophene...)
Show SMILES CSc1sc(cc1S(=O)(=O)c1cccc(c1)-c1ccccc1)C(N)=N
Show InChI InChI=1S/C18H16N2O2S3/c1-23-18-16(11-15(24-18)17(19)20)25(21,22)14-9-5-8-13(10-14)12-6-3-2-4-7-12/h2-11H,1H3,(H3,19,20)
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Article
PubMed
 260n/an/an/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of Complement C1s subcomponent

Bioorg Med Chem Lett 18: 1603-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.064
BindingDB Entry DOI: 10.7270/Q2K35TD4
More data for this
Ligand-Target Pair