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SMILES: CSc1sc(cc1S(=O)(=O)c1cccc(c1)-c1ccc(O)cc1)C(N)=N

InChI Key: InChIKey=DBABKKXPOIODOB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50233678   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Complement C1s subcomponent


(Homo sapiens (Human))		BDBM50233678
PNG
(4-(4'-hydroxy-biphenyl-3-sulfonyl)-5-methylsulfany...)
Show SMILES CSc1sc(cc1S(=O)(=O)c1cccc(c1)-c1ccc(O)cc1)C(N)=N
Show InChI InChI=1S/C18H16N2O3S3/c1-24-18-16(10-15(25-18)17(19)20)26(22,23)14-4-2-3-12(9-14)11-5-7-13(21)8-6-11/h2-10,21H,1H3,(H3,19,20)
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Article
PubMed
 190n/an/an/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of Complement C1s subcomponent

Bioorg Med Chem Lett 18: 1603-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.064
BindingDB Entry DOI: 10.7270/Q2K35TD4
More data for this
Ligand-Target Pair