BDBM50233697 4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(piperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide::CHEMBL399763

SMILES: CN1CCN(CC1)c1ccc(NC(=O)c2cc(c[nH]2)C#N)c(c1)N1CCCCC1

InChI Key: InChIKey=NZRFILSWDBFAQV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50233697   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony stimulating factor receptor (Homo sapiens (Human))	BDBM50233697 (4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(piperidin...) Show SMILES CN1CCN(CC1)c1ccc(NC(=O)c2cc(c[nH]2)C#N)c(c1)N1CCCCC1 Show InChI InChI=1S/C22H28N6O/c1-26-9-11-27(12-10-26)18-5-6-19(21(14-18)28-7-3-2-4-8-28)25-22(29)20-13-17(15-23)16-24-20/h5-6,13-14,16,24H,2-4,7-12H2,1H3,(H,25,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic FMS expressed in Sf9-baculovirus system after 80 mins by fluorescence polarization				Bioorg Med Chem Lett 18: 1642-8 (2008) Article DOI: 10.1016/j.bmcl.2008.01.059 BindingDB Entry DOI: 10.7270/Q2FB52PS
					More data for this Ligand-Target Pair
Macrophage colony stimulating factor receptor (Homo sapiens (Human))	BDBM50233697 (4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(piperidin...) Show SMILES CN1CCN(CC1)c1ccc(NC(=O)c2cc(c[nH]2)C#N)c(c1)N1CCCCC1 Show InChI InChI=1S/C22H28N6O/c1-26-9-11-27(12-10-26)18-5-6-19(21(14-18)28-7-3-2-4-8-28)25-22(29)20-13-17(15-23)16-24-20/h5-6,13-14,16,24H,2-4,7-12H2,1H3,(H,25,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of FMS mediated phosphorylation using SYEGNSYTFIDPTQ as substrate after 80 mins by fluorescence polarization				J Med Chem 54: 7860-83 (2011) Article DOI: 10.1021/jm200900q BindingDB Entry DOI: 10.7270/Q2VD70JB
					More data for this Ligand-Target Pair