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SMILES: CC1CCN(CC1)c1cc(ccc1NC(=O)c1ccc(o1)C#N)N1CCN(CC1)S(C)(=O)=O

InChI Key: InChIKey=REJFXXBFQUSFTH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50233713   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))		BDBM50233713
PNG
(5-cyano-N-(2-(4-methylpiperidin-1-yl)-4-(4-(methyl...)
Show SMILES CC1CCN(CC1)c1cc(ccc1NC(=O)c1ccc(o1)C#N)N1CCN(CC1)S(C)(=O)=O
Show InChI InChI=1S/C23H29N5O4S/c1-17-7-9-27(10-8-17)21-15-18(26-11-13-28(14-12-26)33(2,30)31)3-5-20(21)25-23(29)22-6-4-19(16-24)32-22/h3-6,15,17H,7-14H2,1-2H3,(H,25,29)
PDB

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antibodypedia
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UniChem

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Article
PubMed
n/an/a 0.900n/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL


Assay Description
Inhibition of human cytoplasmic FMS expressed in Sf9-baculovirus system after 80 mins by fluorescence polarization

Bioorg Med Chem Lett 18: 1642-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.059
BindingDB Entry DOI: 10.7270/Q2FB52PS
More data for this
Ligand-Target Pair