BDBM50233996 CHEMBL4073407

SMILES: CCCCCCCCCCNc1ccnc(NCCN(C)C)n1

InChI Key: InChIKey=ZUMMABQMAJHRGO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50233996   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dynamin-2 (Homo sapiens (Human))	BDBM50233996 (CHEMBL4073407) Show SMILES CCCCCCCCCCNc1ccnc(NCCN(C)C)n1 Show InChI InChI=1S/C18H35N5/c1-4-5-6-7-8-9-10-11-13-19-17-12-14-20-18(22-17)21-15-16-23(2)3/h12,14H,4-11,13,15-16H2,1-3H3,(H2,19,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of dynamin 2 in human U2OS cells assessed as reduction in clathrin-mediated endocytosis by measuring transferrin-A594 uptake preincubated ...				J Med Chem 60: 349-361 (2017) BindingDB Entry DOI: 10.7270/Q27M0B6T
					More data for this Ligand-Target Pair