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BDBM50234019 CHEMBL4096268

SMILES: Clc1ccccc1OC[C@@H]1CCCN1c1ncnc2[nH]cnc12

InChI Key: InChIKey=YJVSNGVKQCPVFF-NSHDSACASA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50234019   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Microtubule-associated protein 2


(Homo sapiens (Human))		BDBM50234019
PNG
(CHEMBL4096268)
Show SMILES Clc1ccccc1OC[C@@H]1CCCN1c1ncnc2[nH]cnc12 |r|
Show InChI InChI=1S/C16H16ClN5O/c17-12-5-1-2-6-13(12)23-8-11-4-3-7-22(11)16-14-15(19-9-18-14)20-10-21-16/h1-2,5-6,9-11H,3-4,7-8H2,(H,18,19,20,21)/t11-/m0/s1
KEGG

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Inhibition of recombinant human N-terminal His tagged MetAP-2 using tripeptide Met-Ala-Ser as substrate preincubated for 15 mins followed by substrat...

Bioorg Med Chem Lett 27: 551-556 (2017)


BindingDB Entry DOI: 10.7270/Q2V98BB4
More data for this
Ligand-Target Pair