BDBM50234022 CHEMBL4066295

SMILES: N#Cc1ccc(OC[C@H]2CCCN2c2ncnc3[nH]cnc23)cc1

InChI Key: InChIKey=DHBAKAQBDBGGTK-CYBMUJFWSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50234022   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microtubule-associated protein 2 (Homo sapiens (Human))	BDBM50234022 (CHEMBL4066295) Show SMILES N#Cc1ccc(OC[C@H]2CCCN2c2ncnc3[nH]cnc23)cc1 |r| Show InChI InChI=1S/C17H16N6O/c18-8-12-3-5-14(6-4-12)24-9-13-2-1-7-23(13)17-15-16(20-10-19-15)21-11-22-17/h3-6,10-11,13H,1-2,7,9H2,(H,19,20,21,22)/t13-/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His tagged MetAP-2 using tripeptide Met-Ala-Ser as substrate preincubated for 15 mins followed by substrat...				Bioorg Med Chem Lett 27: 551-556 (2017) BindingDB Entry DOI: 10.7270/Q2V98BB4
					More data for this Ligand-Target Pair