BDBM50234027 CHEMBL4086033

SMILES: Clc1ccccc1OC[C@H]1CCCN1c1ccnc2[nH]cnc12

InChI Key: InChIKey=GQTJSFHRVMRHGH-GFCCVEGCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50234027   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microtubule-associated protein 2 (Homo sapiens (Human))	BDBM50234027 (CHEMBL4086033) Show SMILES Clc1ccccc1OC[C@H]1CCCN1c1ccnc2[nH]cnc12 |r| Show InChI InChI=1S/C17H17ClN4O/c18-13-5-1-2-6-15(13)23-10-12-4-3-9-22(12)14-7-8-19-17-16(14)20-11-21-17/h1-2,5-8,11-12H,3-4,9-10H2,(H,19,20,21)/t12-/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His tagged MetAP-2 using tripeptide Met-Ala-Ser as substrate preincubated for 15 mins followed by substrat...				Bioorg Med Chem Lett 27: 551-556 (2017) BindingDB Entry DOI: 10.7270/Q2V98BB4
					More data for this Ligand-Target Pair