BDBM50234029 CHEMBL4091303

SMILES: Clc1ccccc1OC[C@H]1CCCN1c1ncnc2ncccc12

InChI Key: InChIKey=RXSMJUIGEXUBGW-CYBMUJFWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50234029   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microtubule-associated protein 2 (Homo sapiens (Human))	BDBM50234029 (CHEMBL4091303) Show SMILES Clc1ccccc1OC[C@H]1CCCN1c1ncnc2ncccc12 |r| Show InChI InChI=1S/C18H17ClN4O/c19-15-7-1-2-8-16(15)24-11-13-5-4-10-23(13)18-14-6-3-9-20-17(14)21-12-22-18/h1-3,6-9,12-13H,4-5,10-11H2/t13-/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His tagged MetAP-2 using tripeptide Met-Ala-Ser as substrate preincubated for 15 mins followed by substrat...				Bioorg Med Chem Lett 27: 551-556 (2017) BindingDB Entry DOI: 10.7270/Q2V98BB4
					More data for this Ligand-Target Pair